Newspaper Page Text
Patient Information
BYtl lA® (bye-A-tuh)
exenatide injection
Read this Patient Information and the Pen User Manual that come with BYFTTA
before you start using it and each time you get a refill. There may be new
information. This Patient Information does not take the place of talking with your
healthcare provider about your medical condition or your treatment. If you have
questions about BYETTA after reading this information, ask your healthcare
provider or pharmacist.
What is BYETTA?
BYETTA is an injectable medicine used to improve glucose (blood sugar) control in
adults with type 2 diabetes. BYETTA can be used with metformin, a sulfonylurea, or a
thiazoMinedione. There are many antidiabetic medicines that contain a sulfonylurea.
Ask your healthcare provider or pharmacist if you are not sure if your antidiabetic
medicine contains a sulfonylurea
BYETTA is not a substitute for insulin in patients whose diabetes requires insulin
treatment BYETTA has not been studied in children
Who should not use BYETTA?
Do not use BYETTA if:
• You are allergic to exenatide or any of the other ingredients in BYETTA See the
end of this Patient Infoimation foi a complete list of ingredients
What should I tell my healthcare provider before using BYETTA?
Tell your healthcare provider about all of your medical conditions including if you:
• Have severe problems with your stomach (gastroparesis) or food digestion. BYETTA
slows stomach emptying so food passes more slowly through your stomach.
• Have severe kidney disease or you are on dialysis
• Are pregnant or planning to become pregnant. It s not known if BYETTA may
harm your unborn child.
• Are breastfeeding It is not known if BYETTA passes into your milk and can harm
your child.
Tell yout healthcare provider about all the medicines you take including
prescription and nonprescription medicines, vitamins, and herbal supplements.
BYETTA slows stomach emptying and can affect medicines that need to pass
through the stomach quickly. Ask your liealthcare provider if the time at which you
take any of your oral medicines (for example, birth control pills, antibiotics) should
be changed.
Know the medicines you take. Keep a list of them with you to show your healthcare
provider and pharmacist each tune you get a new medicine.
How should I use BYETTA?
See the accompanying Pen User Manual for instructions for using the BYETTA
Pen and injecting BYETTA. BYETTA comes in a prefilied pen. Two prefilled pens
(5 meg or 10 meg) are available, depending on your presenbed dose (5 meg or
10 meg, twice a day) Each pen has 60 doses to provide 30 days of twice-a-day
injections. You must do a "New Pen Set-Up’ (see User Manual) one time only,
when starting a new prefilied BYETTA Pen. If you do this “New Pen Set-Up" before
each injection, you will run out of medicine before 30 days.
• Use BYETTA exactly as prescribed by your healthcare provider Your dose may be
increased after using BYETTA for 30 days. Do not change your dose unless your
healthcaie provider has told you to change your dose. Your healthcare provider
must teach you how to in|ect BYETTA before you use it for the first time If you
have questions or do not understand the instructions, talk to your healthcare
provider or pharmacist
• Pen needles are not included. You may need a prescnption to purchase pen
needles from your pharmacist. Ask your healthcaie provider which needle length
and gauge is best for you
• Inject your dose of BYETTA under the skin (subcutaneous injection) of your upper
leg (thigh), stomach are 3 (abdomen), or upper arm
• BYETTA is injected, twice a day, at any time within the 60 minutes (I hour) before
your morning and evening meals (or before the two main meals of the day,
approximately 6 hours or more apart). Do not take BYETTA after your meal.
BYETTA' exenatide injection 8? 3001 EE
• If you miss a dose of BYETTA, skip that dose and take your next dose at the next
prescribed time. Do not take an extra dose or increase the amount of your
next dose to make up for the one you missed.
• If you use too much BYETTA, call your healthcare provider or poison control center
right away You may need medical treatment right away. Too much BYETTA can
cause nausea, vomiting, dizziness, or symptoms of low blood sugar.
What are the possible side effects of BYETTA?
When BYETTA is used with a medicine that contains a sulfonylurea,
hypoglycemia (low blood sugar) can occur. The dose of your sulfonylurea
medicine may need lo be reduced while you use BYETTA. The signs and symptoms
of low blood sugar may include headache, drowsiness, weakness, dizziness,
confusion, imtabtlity, hunger, fast heartbeat, sweating and feeling jittery Your
healthcare pirovidet should tell you how to treat lorv blood sugar.
The most common side effects with BYETTA include nausea, vomiting diarrhea,
dizziness, headache, Teeling jittery, and acid stomach. Nausea is most common
when first starting BYETTA, but decreases over time in most patients.
BYETTA may reduce your appetite, the amount of food you eat, and your weight.
No changes in your dose are needed for these side effects.
Talk to your healthcare provider about any side effect that bothers you or that does
not go away.
These are not all the side effects with BYETTA Ask your healthcare provider or
pharmacist tot more information.
How should I store BYETTA?
• Store your new, unused BYETTA Pen in the original carton in a refrigerator at 36°F
to 46°F (2°C to B°C) protected from light. Do not freeze. Ihrow away any BYETTA
Pen that has been frozen
• After first use, your BYETTA Pen can be kept at a temperature not to exceed 77°F
(25°C) Do not freeze. Do not use BYFTTA if it has been frozen. BYFTTA should
be protected from light.
• Use a BYETTA Pen for only 30 days Throw away a used BYETTA Pen after
30 days, even if some medicine remains in the pen.
• BYETTA sliould not be used after the expiration date printed on the label.
• Do not store the BYETTA Pen with the needle attached. If the needle is left
on, medicine may leak from the BYETTA Pen or air bubbles may form in the
cartridge.
• Keep your BYETTA Pen, pen needles, and all medicines out of the reach
of children.
General information about BYETTA
Medicines are sometimes prescribed for conditions that are not listed in the Patient
Information Do not use BYETTA for a condition for which it was not prescribed.
Do not give BYETTA to other people, even if they have the same symptoms you
have. It may harm them.
Your food and exercise plan, along with your periodic blood sugar testing and
scheduled AIC (also known as HbA ) checks, will continue to be important in
managing your diabetes while you are taking BYETTA.
This Patient Information indudes the most important information you should know
about using BYETTA. If you would like more information, talk with your healthcare
provider You can ask your healthcare provider or pharmacist tor information about
BYFTTA that is written for health professionals.
• More information on BYETTA can be found at http://www.BYETTA.com.
• BYETTA Customer Service is available 24 hours a day at 1-800-368-1190.
What are the ingredients in BYETTA?
Active Ingredient: exenatide
Inactive Ingredients: metacresol, mannitol, glacial acetic acid, and sodium acetate
tnhydrate in water for injection.
Manufactured for Amylin Pharmaceuticals, Inc., Sail Diego, CA 92121
Marketed by Amylin Pharmaceuticals, Inc. and Eli tally and Company
Literature Revised February 2007
BYETTA is a registered trademark of Amylin Pharmaceuticals, Inc.
fe 2007 Amylin Pharmaceuticals, Inc. All tights reserved. 823001-EE
02-OST4O/-E
BYETTA" exenatide injection 823001-EE
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The Roundstone family is all smiles on the
big day that their new house is completed.
(Continued from page 5)
erty," Roundsrone reasoned. But deciding
their actions might motivate others to
take similar steps to improve their situa
tions, the couple had a change of heart.
“It's like throwing rocks in calm
water,” Roundstone says. “It will spread,
and our community will experience
positive changes."
Young attributes Red Feather's suc
cess to its dedicated staff volunteers
and the generous financial support of
individuals and corporations, which
donate materials, building supplies and
tools. Volunteers come from around
the world to donate their time during
the four weeks of a typical construction
project, pounding nails, hauling sup
plies, hanging drywall, cutting lumber
and doing cleanup. Donations fund
professional tradesmen, usually from
the community, for specialty work such
as plumbing and electrical.
Jan Waters, a nurse from Atlanta,
has volunteered for four Red Feather
building projects. “You feel as if you
get back so much by giving of your
self," she says. “When you leave, your
heart and soul feel good, and your
spirit is balanced."
Young knows from experience that
an individual can make an enormous
difference. “It’s our responsibility to
assist one another," he says. “We must
ask ourselves what kind of world we
wish to live in, and know that we are
all a vital part of the solution.” 2^
Denise Glaser Malloy lives in Bozeman. Mont.
For more photos and additional
information, click on this story
at www.americanprofile.com
www.americanprofile.com •
Page 6