Newspaper Page Text
PATIENT INFORMATION
Caduet
amlodipine desyiate/atorvastatin calcium
«• ir% lßxmOtaOtaßlM
(CAD-00-ct)
Read the patient information that comes with
CADUET before you start taking it, and each time
you get a refill. There may be new information.
This information does not replace talking with your
doctor about your condition or treatment. If you
have any questions about CADUET, ask your doctor
or pharmacist.
What is CADUET?
CADUET is a prescription drug that combines
Norvasc* (amlodipine besylate) and Lipitor®
(atorvastatin calcium) in one pill.
CADUET is used in adults who need both Norvasc
and Lipitor.
Norvasc is used to treat:
• High blood pressure (hypertension) and
• Chest pain (angina) and
• Slocked arteries of the heart (coronary artery
disease)
Lipitor is used to lower the levels of “bad" choles
terol and triglycerides in your blood. It can also
raise the levels of “good” cholesterol.
Lipitor is also used to lower the risk for heart
attack or stroke in patients who have risk factors
for heart disease such as:
• age, smoking, high blood pressure, low HDL-C,
heart disease in the family, or
• diabetes with risk factor such as eye problems,
kidney problems, smoking, or high blood pressure
CADUET has not been studied in children.
Who should not use CADUET?
Do not use CADUET it you:
• Are pregnant or think you may be pregnant, or
are planning to become pregnant. CADUET may
harm your unborn baby. If you get pregnant, stop
taking CADUET and call your doctor right away.
• Are breastfeeding. CADUET can pass into your
breast milk and may harm your baby. Do not
breastfeed if you take CADUET.
• Have liver problems.
• Are allergic to anything in CADUET. The active
ingredients are atorvastatin calcium and
amlodipine besylate. See the end of this leaflet
for a complete list of ingredients.
What should I tell my doctor before taking
CADUET?
Tell your doctor about all of your health
conditions, including, if you have:
• heart disease
• muscle aches or weakness
• diabetes
• thyroid problems
• kidney problems
• or drink more than 2 glasses of alcohol daily
Tell your doctor about all the medicines you take
including prescription and nonprescription medicines,
vitamins and herbal supplements. CADUET and
some other medicines can interact, causing sehous
side effects. Especially tell your doctor if you take
medicines for:
• your immune system • birth control
• infections • heart failure
• cholesterol • HIV (AIDS)
You can use nitroglycerin and CADUET together. If
you take nitroglycerin for chest pain (angina), do
not stop taking it while taking CADUET.
Know all the medicines you take. Keep a list of
them with you to show your doctor and pharmacist.
How should I take CADUET?
• Take CADUET once a day, exactly as your doctor
tells you. Do not change your dose or stop
CADUET without talking to your doctor.
• Take CADUET each day at any time of day. at
about the same time each day. CADUET can be
taken with or without food.
• Do not break the tablets before taking them.
Talk to your doctor if you have a problem
swallowing pills.
• Your doctor should start you on a low-fat diet
before giving you CADUET. Stay on this low-fat
diet when you take CADUET.
• CADUET comes in many different strengths. Your
doctor will test your cholesterol and blood pressure
to find the right dose for you.
• If you miss a dose, take it as soon as you
remember. Do not take CADUET if it has been
more than 12 hours since your missed dose.
Just take the next dose at your regular time. Do
not take 2 doses of CADUET at the same time.
• If too much CADUET is taken by accident, call
your doctor or poison control center, or go to the
nearest emergency room.
What should I avoid while taking CADUET?
• Avoid getting pregnant. If you get pregnant, stop
taking CADUET right away and call your doctor.
• Do not breastfeed. CADUET can pass into your
breast milk and may harm your baby.
What are possible side effects of CADUET?
CADUET can cause serious side effects. These
side effects happen only to a small number of
people. Your doctor can monitor you for them.
These side effects usually go away if your dose
is lowered or CADUET is stopped. These serious
side effects include:
• Muscle problems. CADUET can cause serious
muscle problems that can lead to kidney problems,
including kidney failure. You have a higher
chance for muscle problems if you are taking
certain other medicines with CADUET.
• Liver problems. CADUET can cause liver problems.
Your doctor may do blood tests to check your liver
before you start taking CADUET and while you take it.
Call your doctor right away if:
• you have muscle problems like weakness, tender
ness. or pain that happen without a good reason,
especially if you also have a fever or feel more
tired than usual
• you have nausea and vomiting, stomach pain
• you are passing brown or dark-colored urine
• you feel more tired than usual
• your skin and white of your eyes get yellow
• Chest pain that does not go away or gets worse.
Sometimes, when you start CADUET or increase
your dose, chest pain can get worse or a heart
attack can happen. If this happens, call your
doctor or go to the emergency room right away.
Common side effects of CADUET include:
• headache • dizziness
• tiredness • extreme sleepiness
• stomach pain • nausea
• gas • rash
• constipation • diarrhea
• swelling of your legs or ankles (edema)
• hot or warm feeling in your face (flushing)
• irregular heartbeat (arrhythmia)
• very fast heartbeat (heart palpitations)
• muscle and joint pain
Talk to your doctor or pharmacist about side
effects that bother you or do not go away. There
are other side effects of CADUET. Ask your doctor
or pharmacist for a complete list.
How do I store CADUET?
• Store CADUET at room temperature, 68 to 77°F
(20 to 25°C).
• Do not keep medicine that is out-of-date or that
you no longer need.
• Keep CADUET and all medicines out of the
reach of children. Keep medicines in places
where children cannot get it.
General information about CADUET
Medicines are sometimes prescribed for conditions
that are not mentioned in patient information
leaflets. Do not use CADUET for a condition for
which it was not prescribed. Do not give CADUET
to other people, even if they have the same problem
you have. It may harm them.
This leaflet summarizes the most important informa
tion about CADUET. If you want more information, talk
with your doctor. Ask your doctor or pharmacist for
information about CADUET written for health profes
sionals. You can also go to the CADUET website at
www.CADUET.com. or call 866-514-0900.
What is high blood pressure (hypertension)?
You have high blood pressure when the force of
blood against the walls of your arteries stays high.
This can damage your heart and other parts of
your body. Drugs that lower blood pressure lower
your risk of having a stroke or heart attack.
What is anoina (chest paint?
Angina is a pain that keeps coming back when part
of your heart does not get enough blood. It feels
like something is pressing or squeezing your chest
under the breastbone. Sometimes you can feel it in
your shoulders, arms, neck, jaw, or back.
What is cholesterol?
Cholesterol is a fat-like substance made in your
body. It is also found in foods. You need some
cholesterol for good health, but too much is not good
for you. Cholesterol can clog your blood vessels.
What is a heart attack?
A heart attack occurs when heart muscle does not
get enough blood. Symptoms include chest pain,
trouble breathing, nausea, and weakness. Heart
muscle cells may be damaged or die. The heart
cannot pump well or may stop beating.
What is a stroke?
A stroke occurs when nerve cells in the brain do
not get enough blood. The cells may be damaged
or die. The damaged cells may cause weakness or
problems speaking or thinking.
WHAT ARE THE INGREDIENTS IN CADUET?
Active ingredients: amlodipine besylate,
atorvastatin calcium
Inactive ingredients: calcium carbonate,
croscarmellose sodium, microcrystalline cellulose,
pregelatinized starch, polysorbate 80, hydroxypropyl
cellulose, purified water, colloidal silicon dioxide
(anhydrous), magnesium stearate
Film coating: Opadry* II White 85F28751 (polyvinyl
alcohol, titanium dioxide, PEG 3000 and talc) or
Opadry® II Blue 85F10919 (polyvinyl alcohol, titanium
dioxide, PEG 3000, talc, and FD&C blue #2)
Rx only
Manufactured by Pfizer Ireland Pharmaceuticals
Dublin, Ireland
Distributed by
Pfizer Labs
Division of Pfizer Inc. NY. NY 10017
LAB-0347-2.0
Issued August 2006
© 2006 Pfizer Inc. All rights reserved. CTUOOOI4E
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STICKDOKU ANSWERS:
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